As part of the ARPA-H APECx initiative, and led by PI Byung-Jun Yoon of Texas A&M, SPHERICAL (Scientific Platform for High Efficacy antigen design via Robust Integration of Computational experiments, AI, and protein modeLing) aims to accelerate the prediction of novel antigens with broad viral efficacy (ARPA-H).

The UT-Knoxville team in the MADBio Lab is leading the development of a multiscale computational workflow for mapping molecular activity to functional outcomes in immunogen design.