Predicting Inter-individual Variability During Lipid Resuscitation of Bupivacaine Cardiotoxicity in Rats: A Virtual Population Modeling Study

M. McDaniel, K. Flores, B. Akpa

Drugs in R&D, 2021

Confusion About Infusion: Rational Volume Limits for Intravenous Lipid Emulsion During Treatment of Oral Overdoses.

Michael R Fettiplace, B. Akpa, I. Rubinstein, G. Weinberg

Annals of emergency medicine, 2015

Multi-modal contributions to detoxification of acute pharmacotoxicity by a triglyceride micro-emulsion.

Michael R Fettiplace, K. Lis, Richard Ripper, K. Kowal, A. Pichurko, D. Vitello, I. Rubinstein, David E. Schwartz, B. Akpa, G. Weinberg

Journal of Controlled Release, 2015

Resuscitation with Lipid Emulsion: Dose-dependent Recovery from Cardiac Pharmacotoxicity Requires a Cardiotonic Effect

Michael R Fettiplace, B. Akpa, Richard Ripper, B. Zider, Jason Lang, I. Rubinstein, G. Weinberg

Anesthesiology, 2014

Validity of the Lipid Sink as a Mechanism for the Reversal of Local Anesthetic Systemic Toxicity: A Physiologically Based Pharmacokinetic Model Study

I. Kuo, B. Akpa

Anesthesiology, 2013

Lipid resuscitation: a life-saving antidote for local anesthetic toxicity.

S. Bern, B. Akpa, I. Kuo, G. Weinberg

Current pharmaceutical biotechnology, 2011